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A close-up image of a blister pack with tadalafil tablets, accompanied by a glass of water and a clock, symbolizing timing and dosage.

Recommended Dosage of Tadalafil for Erectile Dysfunction

2 min read
Sources (7)
healthmedicinemen's health

Summary

Tadalafil, known as Cialis, treats ED, BPH, and pulmonary hypertension by increasing blood flow to the penis. Dosage varies: daily (2.5-5mg) or as-needed (10-20mg). Factors like age and health affect dosage. Avoid exceeding one dose/day. Side effects include headache and back pain. Seek help for severe reactions.

Understanding Tadalafil and Erectile Dysfunction

Tadalafil, commonly known by its brand name Cialis, is a medication used to treat erectile dysfunction (ED), benign prostatic hyperplasia (BPH), and pulmonary arterial hypertension. It belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors, which work by inhibiting the enzyme PDE5 to increase blood flow to the penis during sexual arousal.

How Tadalafil Works

Tadalafil works by relaxing blood vessels in the penis, allowing for increased blood flow when sexually aroused. This process is essential for achieving and maintaining an erection sufficient for sexual activity.

Daily Dosing

For patients who prefer daily medication:

  • Starting dose: 2.5mg once daily
  • May be increased to 5mg based on effectiveness and tolerability
  • Take at approximately the same time each day
  • No timing restrictions relative to sexual activity

As-Needed Dosing

For occasional use:

  • Initial dose: 10mg taken prior to anticipated sexual activity
  • Maximum dose: 20mg if needed
  • Take at least 30 minutes before sexual activity
  • Effects can last up to 36 hours

Factors Affecting Dosage

Several considerations influence the appropriate dosage:

  • Age
  • Kidney function
  • Liver function
  • Other medications
  • Overall health status

Special Populations

Creatinine Clearance Recommended Dose 30-50 mL/min Maximum 5mg daily <30 mL/min Maximum 2.5mg daily

Important Considerations

Never exceed one dose per day, regardless of dosing regimen chosen.

Timing and Usage Tips

  • Can be taken with or without food
  • Limit alcohol consumption
  • Allow sufficient time before sexual activity
  • For daily dosing, maintain consistent timing

Drug Interactions

Tadalafil can interact with:

  1. Nitrates for chest pain
  2. Alpha blockers
  3. Antifungal medications
  4. HIV protease inhibitors
  5. Other ED medications

Side Effects

Common side effects include:

  • Headache
  • Indigestion
  • Back pain
  • Muscle aches
  • Flushing
  • Nasal congestion

Emergency Situations

Seek immediate medical attention if experiencing:

  • Vision changes
  • Hearing problems
  • Prolonged erection (>4 hours)
  • Chest pain

Medical Precautions

Before taking tadalafil, inform your healthcare provider if you have:

  • Heart disease
  • High or low blood pressure
  • Liver or kidney disease
  • A history of stroke

For more detailed information, visit resources like the Mayo Clinic, Drugs.com, or the FDA medication guide.

Sources

WCialishttps://www.lilly.com/our-medicines/historic-medicinesWMayo Clinichttps://www.mayoclinic.org/drugs-supplements/tadalafil-oral-route/description/drg-20066970WDrugs.comhttps://www.drugs.com/tadalafil.htmlWFDA medication guidehttps://www.fda.gov/drugs/fdas-labeling-resources-human-prescription-drugs/patient-labeling-resourcesWCialishttps://www.cialis.com/WFDA medication guidehttps://www.fda.gov/drugsWNational Institute of Diabetes and Digestive and Kidney Diseaseshttps://www.niddk.nih.gov/