Recommended Dosage of Tadalafil for Erectile Dysfunction

## Understanding Tadalafil and Erectile Dysfunction Tadalafil, commonly known by its brand name [Cialis](https://www.lilly.com/our-medicines/historic-medicines), is a medication used to treat erectile dysfunction (ED), benign prostatic hyperplasia (BPH), and pulmonary arterial hypertension. It belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors, which work by inhibiting the enzyme PDE5 to increase blood flow to the penis during sexual arousal. ## How Tadalafil Works Tadalafil works by relaxing blood vessels in the penis, allowing for increased blood flow when sexually aroused. This process is essential for achieving and maintaining an erection sufficient for sexual activity. ## Recommended Dosage Options ### Daily Dosing For patients who prefer daily medication: - Starting dose: 2.5mg once daily - May be increased to 5mg based on effectiveness and tolerability - Take at approximately the same time each day - No timing restrictions relative to sexual activity ### As-Needed Dosing For occasional use: - Initial dose: 10mg taken prior to anticipated sexual activity - Maximum dose: 20mg if needed - Take at least 30 minutes before sexual activity - Effects can last up to 36 hours ## Factors Affecting Dosage Several considerations influence the appropriate dosage: * Age * Kidney function * Liver function * Other medications * Overall health status ### Special Populations ``` Creatinine Clearance Recommended Dose 30-50 mL/min Maximum 5mg daily Never exceed one dose per day, regardless of dosing regimen chosen. ### Timing and Usage Tips - Can be taken with or without food - Limit alcohol consumption - Allow sufficient time before sexual activity - For daily dosing, maintain consistent timing ### Drug Interactions Tadalafil can interact with: 1. Nitrates for chest pain 2. Alpha blockers 3. Antifungal medications 4. HIV protease inhibitors 5. Other ED medications ## Side Effects Common side effects include: - Headache - Indigestion - Back pain - Muscle aches - Flushing - Nasal congestion ### Emergency Situations **Seek immediate medical attention** if experiencing: - Vision changes - Hearing problems - Prolonged erection (>4 hours) - Chest pain ## Medical Precautions Before taking tadalafil, inform your healthcare provider if you have: - Heart disease - High or low blood pressure - Liver or kidney disease - A history of stroke For more detailed information, visit resources like the [Mayo Clinic](https://www.mayoclinic.org/drugs-supplements/tadalafil-oral-route/description/drg-20066970), [Drugs.com](https://www.drugs.com/tadalafil.html), or the [FDA medication guide](https://www.fda.gov/drugs/fdas-labeling-resources-human-prescription-drugs/patient-labeling-resources).

Recommended Dosage of Tadalafil for Erectile Dysfunction

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