What is Augmentin?
Augmentin is a widely prescribed antibiotic that combines two active ingredients:
- Amoxicillin: A penicillin-type antibiotic that kills bacteria
- Clavulanic acid (clavulanate potassium): A beta-lactamase inhibitor that prevents bacteria from destroying amoxicillin
This combination makes it effective against a broader spectrum of bacterial infections compared to amoxicillin alone by preventing certain bacteria from becoming resistant.
Common Uses
Respiratory Tract Infections
- Sinusitis
- Pneumonia
- Bronchitis
- Tonsillitis
- Middle ear infections (particularly in children)
Other Applications
- Skin and soft tissue infections (cellulitis, impetigo, abscesses)
- Urinary tract infections (UTIs)
- Dental infections
- Post-surgical infection prevention
According to the Centers for Disease Control and Prevention (CDC), Augmentin is effective against various bacterial pathogens, including Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis.
Proper Dosage
The dosage varies based on several factors:
- Age of patient
- Type and severity of infection
- Kidney function
- Body weight (especially in children)
Common Adult Dosages
| Infection Severity | Typical Dose | Frequency |
|---|---|---|
| Mild to Moderate | 875/125 mg | Every 12 hours |
| Severe | 875/125 mg | Every 8 hours |
Children's Dosage
The dosage is usually 25-45 mg/kg/day divided into two doses, based on the child's weight.
Important: Always follow your healthcare provider's specific dosing instructions, as they may differ from standard recommendations.
Taking Augmentin Correctly
For optimal results:
- Take with food to minimize stomach upset
- Complete the entire prescribed course
- Space doses evenly throughout the day
- Store at room temperature
- Check expiration dates
Side Effects
Common Side Effects
- Diarrhea
- Nausea and vomiting
- Skin rash
- Abdominal pain
- Headache
- Vaginal yeast infection
Serious Side Effects
Seek immediate medical attention if you experience:
- Severe allergic reactions (hives, difficulty breathing, swelling of face/throat)
- Severe diarrhea (watery or bloody stools)
- Yellowing of skin or eyes (jaundice)
- Unusual bleeding or bruising
- Severe skin reactions
- Liver or kidney damage
For a comprehensive list of side effects, visit Drugs.com's Augmentin page.
Drug Interactions and Precautions
Before taking Augmentin, inform your doctor about any allergies or if you're taking:
- Blood thinners (warfarin)
- Birth control pills
- Allopurinol
- Probenecid
- Other antibiotics
- Proton pump inhibitors
- Methotrexate
Special Considerations
Patients should use caution if they have:
- Penicillin or cephalosporin allergies
- Liver problems
- Kidney disease
- Mononucleosis
Pregnancy and Nursing
Augmentin is generally considered safe during pregnancy (Category B), but consult your healthcare provider for personalized advice.
For more detailed information, visit the FDA medication guide, Mayo Clinic's page on Augmentin, or MedlinePlus.